Input COG Number

PhyloCOG is a database of protein evolution knowledge derived from the COGs. The focus is on gaining an outline of the most ancient protein families. In addition to traditional parsimony information which can be used to assess pre-archaea:bacteria evolutionary history (conserved presence and phylogeny), PhyloCOG reports data on the evolutionary distance between domains, in comparison to evolutionary distances within domains.

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Please cite the following reference:

Sarah J Berkemer and Shawn E McGlynn. (2020) A New Analysis of Archaea–Bacteria Domain Separation: Variable Phylogenetic Distance and the Tempo of Early Evolution. Molecular Biology and Evolution, Volume 37, Issue 8, August 2020, Pages 2332–2340.

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